Pets and their owners alike will be excited by the convenience of Advantage Multi® for Dogs (imidacloprid + moxidectin) Topical Solution. Your veterinarian will determine the correct dosage for your dog by his/her weight. Once a month, the pre-measured dose is applied to the surface of the dog's skin.
Advantage Multi for Dogs is available in the four different sizes:
The recommended minimum dose is 4.5mg/lb (10.0 mg/kg) imidacloprid and 1.1 mg/lb (2.5 mg/kg) moxidectin, once a month by topical administration.
Do not apply to irritated skin

* Dogs over 88 lbs. should be treated with the appropriate combination of Advantage Multi for Dogs tubes.
For dogs weighing 20 lbs. or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades.

For dogs weighing more than 20 lbs., place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at three or four spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking.

Do not let this product get in your dog's mouth or eyes.
Do not allow the dog to lick any of the application sites for 30 minutes. In households with multiple pets, keep each treated dog separated from other treated dogs and other pets for 30 minutes after application to prevent licking the application sites. (See indications and warnings)
Stiff hair, a damp appearance of hair, pink skin or a slight powdery residue may be observed at the application site on some animals. This is temporary and does not affect the safety and effectiveness of the product.
Shampooing 90 minutes after treatment does not reduce effectiveness in the prevention of heartworm disease.
Shampooing or water immersion four days after treatment will not reduce the effectiveness in the treatment of flea infestations. However, shampooing as often as once weekly may reduce the effectiveness of the product against fleas.
Warning:
For the first 30 minutes after application:
Ensure that dogs cannot lick the product from application sites on themselves or other treated dogs, and separate treated dogs from one another and from other pets to reduce the risk of accidental ingestion. Ingestion of this product by dogs may cause serious adverse reactions including depression, salivation, dilated pupils, incoordination, panting, and generalized muscle tremors. In avermectin-sensitive dogs, the signs may be more severe and may include coma and death.1